Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
Verweise:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
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Drug Intermediate Verwandte Produkte (4634)
Verwandte Produkte (4634)
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1-Hydroxy-2-butanone
0 ImagesArt. -Nr.: HY-W005327CAS. Nr.: 5077-67-81-Hydroxy-2-butanone is a natural compound isolated from Bomboo Juice. 1-Hydroxy-2-butanone acts as a key intermediate for ethambutol. Ethambutol has anti-tuberculosis effects.
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(R)-1-[5-Amino-2-(2-benzyloxy-1,1-dimethyl-ethyl)-6-fluoro-indol-1-yl]-3-benzyloxy-propan-2-ol
![(R)-1-[5-Amino-2-(2-benzyloxy-1,1-dimethyl-ethyl)-6-fluoro-indol-1-yl]-3-benzyloxy-propan-2-ol](https://file.medchemexpress.com/product_pic/hy-77931.gif "Click to View (R)-1-[5-Amino-2-(2-benzyloxy-1,1-dimethyl-ethyl)-6-fluoro-indol-1-yl]-3-benzyloxy-propan-2-ol Product Detail")
0 ImagesSynonyms: VX-661 intermediate(R)-1-[5-Amino-2-(2-benzyloxy-1,1-dimethyl-ethyl)-6-fluoro-indol-1-yl]-3-benzyloxy-propan-2-ol (VX-661 intermediate) is a drug intermediate for synthesis of various active compounds.
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NSC 96918
0 ImagesNSC 96918 (Compound 22) is a commonly used building block that can be used to synthesize a variety of active compounds.
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Melevodopa hydrochloride
0 ImagesSynonyms: Levodopa methylester hydrochlorideMelevodopa (Levodopa methylester) hydrochloride is an orally active methylated prodrug of Levodopa (HY-N0304), a dopamine precursor. When used in combination with Carbidopa (HY-B0311) in an effervescent tablet formulation, Melevodopa hydrochloride inhibits motor fluctuations in Parkinson's disease. Melevodopa hydrochloride suppresses subcutaneous tumor growth, pulmonary metastasis proliferation, and primary mass invasiveness of melanoma. Melevodopa hydrochloride induces lipid peroxidation by increasing malondialdehyde levels in melanoma and improves the survival rate of melanoma-bearing mice. Melevodopa hydrochloride can be used in research related to Parkinson's disease (with motor fluctuations) and melanoma.
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Monobenzyl Terephthalate
0 ImagesSynonyms: 4-((Benzyloxy)carbonyl)benzoic acidMonobenzyl Terephthalate (4-((Benzyloxy)carbonyl)benzoic acid) is a drug intermediate for synthesis of various active compounds.
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1,3-Propanesultam
0 ImagesSynonyms: 1,1-Dioxoisothiazolidine1,3-Propanesultam (1,1-Dioxoisothiazolidine) is a cyclic sulfonamide monomer. Polymerization of 1,3-Propanesultam under base catalysis produces high-molecular-weight polypropanesulfonamide, while polymerization under acid catalysis yields low-molecular-weight polypropanesulfonamide. 1,3-Propanesultam serves as a coupling partner in copper-catalyzed C-N cross-coupling reactions for the synthesis of 3-aminopyrazole phenylacetamide analogs. 1,3-Propanesultam is applicable to research related to organic synthesis.
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4-((2-Aminoethyl)(5-chlorobenzo[d]oxazol-2-yl)amino)butan-2-one dimethanesulfonate
![4-((2-Aminoethyl)(5-chlorobenzo[d]oxazol-2-yl)amino)butan-2-one dimethanesulfonate](https://file.medchemexpress.com/product_pic/hy-77004.gif "Click to View 4-((2-Aminoethyl)(5-chlorobenzo[d]oxazol-2-yl)amino)butan-2-one dimethanesulfonate Product Detail")
0 ImagesSynonyms: Suvorexant internate 24-((2-Aminoethyl)(5-chlorobenzo[d]oxazol-2-yl)amino)butan-2-one dimethanesulfonate (Suvorexant internate 2) is a drug intermediate for synthesis of various active compounds.
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Z-Lys-OMe hydrochloride
0 ImagesZ-Lys-OMe hydrochloride is a synthetic intermediate that can be used in the synthesis of peptide enzyme substrates and lysine cationic surfactants.
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2-Bromo-4-chloropyridine
0 Images2-Bromo-4-chloropyridine is a halogenated pyridine derivative that serves as a synthetic intermediate. 2-Bromo-4-chloropyridine undergoes Suzuki-Miyaura coupling with 4-tert-butylphenylboronic acid (HY-W007389). 2-Bromo-4-chloropyridine facilitates the construction of compounds with broad-spectrum antibacterial activity.
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Carbon-13C
0 ImagesArt. -Nr.: HY-Y1213SCAS. Nr.: 14762-74-4Carbon-13C is the 13C labeled Carbon (HY-Y1213). Carbon possesses unique physicochemical properties such as electrical and structural characteristics, making it a core material in the field of fuel cells. Carbon also serves as a pharmaceutical excipient and can be used in the synthesis of other compounds.
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Indole-4-carboxaldehyde
0 ImagesIndole-4-carboxaldehyde is an ergot alkaloid precursor that regulates glycosylation and inflammation. Indole-4-carboxaldehyde upregulates Glo-1, inhibits MGO-induced NF-κB activation, and suppresses MGO-induced expression of TNF-α and IFN-γ. Indole-4-carboxaldehyde inhibits MGO-induced formation of advanced glycation end products (AGE) and expression of their receptor (RAGE). Indole-4-carboxaldehyde is a core metabolite produced in the pedicels of Summer Black grapes after exogenous gibberellin treatment, and it directly promotes fruit enlargement and fruit set of Summer Black grapes. Indole-4-carboxaldehyde can be used in studies related to hepatic steatosis and plant growth regulation.
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PAR-2-IN intermediate-1
0 ImagesPAR-2-IN intermediate-1 is a drug intermediate that can be used to synthesize inhibitors of the PAR-2 signaling pathway.
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Ibrutinib deacryloylpiperidine
0 ImagesSynonyms: IBT4A
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2-Methyl-4-pentenoic Acid
0 ImagesSynonyms: 2-Methylpent-4-enoic acid2-Methyl-4-pentenoic Acid (2-Methylpent-4-enoic acid) is an organic acid that can be used as a precursor for synthesizing other compounds. Additionally, changes in the level of 2-Methyl-4-pentenoic Acid may be associated with the susceptibility to schizophrenia and type 2 diabetes.
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N-Cbz-Hydroxy-L-proline
0 ImagesN-Cbz-Hydroxy-L-proline is a chiral N-Cbz-protected amino acid derivative. N-Cbz-Hydroxy-L-proline is commonly used in the synthesis of polypeptides and pharmaceutical intermediates. N-Cbz-Hydroxy-L-proline undergoes decarboxylation under AlCl3/HFIP conditions.
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Glu-urea-Glu-NHS ester
0 ImagesGlu-urea-Glu-NHS ester is an activated N-hydroxysuccinamide (NHS) ester of Glu-urea-Glu. Glu-urea-Glu-NHS ester can be used for synthesis of small-molecule prostate-specific membrane antigen (PSMA) inhibitors, imaging agents (such as PSMAi-PEG conjugates), and targeted drug delivery vehicles.
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2,5-Dihydroxyterephthalic acid
0 ImagesArt. -Nr.: HY-W004616CAS. Nr.: 610-92-42,5-Dihydroxyterephthalic acid is a carboxylic acid ligand with antioxidant properties, which serves as a building block for Zn2+-based metal-organic frameworks (MOFs). 2,5-Dihydroxyterephthalic acid forms stable coordination bonds with transition metal ions, inhibits metal center-water coordination to prevent MOF fluorescence quenching, and enhances the hydrophilicity of MOFs. 2,5-Dihydroxyterephthalic acid acts as a pharmaceutical intermediate to synthesize 2,5-dihydroxyterephthalamide derivatives. 2,5-Dihydroxyterephthalic acid is applicable to relevant research in fields such as organic synthesis.
